Alla
Rynditch

українська версія
english version

Degree: Taras Shevchenko Kiev State University, Faculty of biology, Diploma with horours. Year awarded: Ph.D. (1970), D.Sci (1990). Degrees: Professor in specialty "Molecular biology" (1995), Correspondent member of National Academy of Sciences of Ukraine (1997). Place of work: Institute of Molecular Biology and Genetics. Present position: Head of the Department of Molecular Oncogenetics.

Major research interests: gene expression, retroviruses, RNA functions and regulation, cell signaling, biomarkers.

Alla V. Rynditch is working in Institute of molecular biology and genetics NASU since it's foundation and she is one of pioneers of molecular biology in the former Soviet Union and Ukraine. Scholarly works of Dr. Rynditch dedicated to the studying of organization and regulation of genes and oncogenes expression. She was the 1st one in the world who started the research of reverse transcription, and she was between the main organizers and executors of international Programmes "Reverse Transcription" and "Revertase-Oncogen". Realization of these programmes has allowed creating of the scientific and technical basis for genetic engineering and development of the fundamental research in the field of molecular oncogenetics.

Prof. Alla Rynditch have actively collaborates with the leading scientific institutions of Italy, France, Czech Republic, Sweden, USA. She have organized and headed a number of international scientific meetings, including the several ones under the UNESCO guidance. Dr. Rynditch represented about forty symposial reports on the international conferences.

Membership: European Association for Cancer Research (EACR), Human Genome Organization (HUGO).

Number of publications: 90 referred papers and 131 conference abstracts.

Tel. lab: +380 44 5263498. Tel. home +380 44 2343727. Fax: +380 44 5263498. E-mail: rynditch@imbg.org.ua.

Selected publications:

  1. Tsyba, L.O., Skrypkina, I.Y., Rynditch, A.V., Nikolaienko, O., Ferenez, G., Fortna, A. and Gardiner K. (2004) Alternative splicing of mammalian Intersectin 1: domain associations and tissue specificities. Genomics, 84, 106-113.
  2. Tsyba, L., Rynditch, A., Boeri, E., Jabbari, K. and Bernardi G. (2004) Distribution of HIV-1 in the genomes of AIDS patients. Cell. Mol. Life Sci., 61, 721-726.
  3. Borisenko, L. and Rynditch, A.V. (2004) Complete nucleotide sequences of ALV-related endogenous retroviruses available from the Draft Chiken Genome Sequence. Folia Biologica, 50, 136-141.
  4. Razin, S., Rynditch, A., Borunova, V., Ioudinkova, E., Smalko, V. and Scherrer, K. (2004) The about 33 kb-long Full Domain Transcript of the Chicken Globin Gene Domain is a Structural Component of the Nuclear Matrix. J. Cell Biochem., 92, 445-457.
  5. Kashuba, V., Kvasha, S., Protopopov, A., Gizatullin, R., Rynditch, A., Wahlestedt, C., Wasserman, W., and Zabarovsky, E. (2001) Initial isolation and analysis of the human Kv1.7 (KCNA7) gene, a member of the voltage-gated potassium channel gene family. Gene, 268, 115-122.
  6. Slavov, D., Hattori, M., Sakaki, Y., Rosenthal, A., Shimizu, N., Minoshima, S., Kudoh, J., Yaspo, M.-L., Ramser, J., Reinhardt, R., Reimer, C., Clancy, K., Rynditch, A., and Gardiner, K. (2000) Criteria for gene identification and features of genome organization: analysis of 6.5 Mb of DNA sequence from human chromosome 21. Gene, 247, 215-232.
  7. Glukhova, L.A., Zoubak, S.V., Rynditch, A.V., Miller, G.G., Titova, I.V., Vorobyeva, N., Lazurkevitch, Z.V., Graphodatskii, A.S., Kushch, A.A., and Bernardi, G. (1999) Localization of HTLV-1 and HIV-1 proviral sequences in chromosomes of persistently infected cells. Chromosome research, 7, 177-183.
  8. Rynditch, A., Zoubak, S., Tsyba, L., Tryapitsina-Guley, N., and Bernardi, G. (1998) The regional integration of retroviral sequences into the mosaic genomes of mammals. Gene, 22, 1-16.
  9. Rynditch, A., Pekarsky, Y., Schnittger, S., and Gardiner, K. (1997) Leukemia breakpoint region in 3q21 is gene rich. Gene, 193, 49-57.
  10. Pekarsky, Y., Rynditch, A., Wieser, R., Fonatch, C., and Gardiner, K. (1997) Activation of a novel gene in 3q21 and identification of intergenic transcripts with EVI1 in leukemia. Cancer Research, 57, 3914-3919.
  11. Pekarsky, Y., Zabarovsky, E., Kashuba, V., Sanberg, A., Morgan, R., Rynditch, A., and Gardiner, K. (1995) Cloning breakpoints in 3q21 associated with hematological malignancy. Cancer Genetics and Cytogenetics, 80, 1-8.